|
My master's research project (1.5 years) at IISER Kolkata was focused on the topic "Radicals in Organic Synthesis". I have learned many aspects of this emerging research field like the principles of photo-catalysts design and carry out photocatalyzed reactions. I also studied and actively worked in other fields of organic chemistry including C-H activation and amino acid modifications.
Relevent Publications:
1) Recent Advances on Amino Acid Modifications via C-H Functionalization and Decarboxylative functionalization Strategies.
S. Mondal; S. Chowdhury* Adv. Synth. Catal, 2018, 360, 1884-1912
2) Visible-light mediated trifluoromethylation of p-quinone methides by 1,6-conjugate addition using pyrylium salt as an organic photocatalyst; K. G. Ghosh, C. Pallasetty, S. Mondal, Sureshkumar*. D; Tetrahedron. 2019, 75, 4471 - 4478
Relevent Publications:
1) Recent Advances on Amino Acid Modifications via C-H Functionalization and Decarboxylative functionalization Strategies.
S. Mondal; S. Chowdhury* Adv. Synth. Catal, 2018, 360, 1884-1912
2) Visible-light mediated trifluoromethylation of p-quinone methides by 1,6-conjugate addition using pyrylium salt as an organic photocatalyst; K. G. Ghosh, C. Pallasetty, S. Mondal, Sureshkumar*. D; Tetrahedron. 2019, 75, 4471 - 4478
Visible light photocatalysis
1) Importance of Fluorination & Trifluoromethylation
C-F and C-CF3 bonds play crucial roles in pharmaceuticals, agrochemicals, and materials due to the high electronegativity of fluorine, influencing various physical properties. Despite over a century of organofluorine chemistry, the formation of C-F and C-CF3 bonds remains challenging. Limited availability of fluorinating reagents, particularly for trifluoromethylation, poses a significant hurdle. Electrophilic trifluoromethylation reagents, although more reactive and more used, are often expensive and labor-intensive to synthesize, contributing to the ongoing difficulties in this field.
For a short period of time, I worked on the project "selective trifluoromethylation of organic compounds from nucleophilic trifluoromethylating source". Our primary goals was to develop new methodology for trifluoromethylation using cheap commercially available nucleophilic trifluoromethylating reagent (example; CF3SO2Na)
For a short period of time, I worked on the project "selective trifluoromethylation of organic compounds from nucleophilic trifluoromethylating source". Our primary goals was to develop new methodology for trifluoromethylation using cheap commercially available nucleophilic trifluoromethylating reagent (example; CF3SO2Na)